Dynamic NMR effects in breast cancer dynamic-contrast-enhanced MRI

Dynamic NMR effects in breast cancer dynamic-contrast-enhanced MRI.

The passage of a vascular-injected paramagnetic contrast reagent (CR) bolus through a region-of-interest affects tissue (1)H(2)O relaxation and thus MR image intensity. For longitudinal relaxation [R(1) identical with (T(1))(-1)], the CR must have transient molecular interactions with water. Because the CR and water molecules are never uniformly distributed in the histological-scale tissue comp...

Automatic Prostate Cancer Segmentation Using Kinetic Analysis in Dynamic Contrast-Enhanced MRI

Background: Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) provides functional information on the microcirculation in tissues by analyzing the enhancement kinetics which can be used as biomarkers for prostate lesions detection and characterization.Objective: The purpose of this study is to investigate spatiotemporal patterns of tumors by extracting semi-quantitative as well as w...

Dynamic contrast - enhanced MRI in cancer REVIEW

Dynamic contrast-enhanced MRI has been proven to be a valuable technique in cancer imaging. The poorly formed and leaky vessels formed during angiogenesis to supply tumors facilitate an increased uptake of intravenously administered contrast agents in comparison to normal vasculature. The use of mathematical modeling techniques on the change in tumor signal intensity as a function of time provi...

Dynamic 18FDG PET/CT and dynamic contrast enhanced MRI of locally advanced breast cancer

DCE-MRI provides information about the perfusion of tumours together with morphological details. Perfusion of tumour could be assessed by dynamic 18FDG PET/CT (dFDG/PET), in addition to metabolic information. This study was planned to compare the semi-quantitative parameters of DCE-MRI) and dFDG/PET in locally advanced breast cancer. Forty patients with LABC underwent DCE-MRI and DFDG/PET study...

Study of lymph nodes with dynamic contrast-enhanced breast MRI